Description

5-Fluoroindole is a versatile fluorinated heterocyclic building block essential for advanced organic synthesis. Its unique structure, featuring an indole scaffold substituted with a fluorine atom, makes it a critical intermediate for developing novel pharmaceuticals and agrochemicals. This high-purity compound is primarily sought by research institutions and industrial manufacturers in the life sciences sector for creating active pharmaceutical ingredients (APIs) and other fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in oncology and central nervous system (CNS) therapies.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the fluorine atom enhances biological activity and stability.
• Material Science Research: Serves as a precursor for organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors.
• Biochemical Research: Employed as a probe or building block in medicinal chemistry for structure-activity relationship (SAR) studies.
• Fluorine Chemistry: A valuable substrate for further functionalization in organofluorine chemistry, enabling the creation of complex fluorinated molecules.

Basic Information

Item	Details
Product Name	5-Fluoroindole
CAS No.	399-52-0
Molecular Formula	C8H6FN
Molecular Weight	135.14 g/mol
Synonyms	5-Fluoro-1H-indole; 1H-Indole, 5-fluoro-; 5-Fluoroindole; 5-FI; 399-52-0; 5-Fluorindole; NSC 404087; 5-Fluor-1H-indol
EINECS	206-933-5

Quality Control

Our 5-Fluoroindole is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, supporting its use in regulated research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat sources and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	62 - 66 °C
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.