Description

2'-Fluoroacetanilide is a specialized fluorinated organic intermediate of significant importance in advanced chemical synthesis. Its core value lies in the strategic incorporation of a fluorine atom into the aniline scaffold, which is a key modification for tuning the biological activity and physicochemical properties of target molecules. This compound is primarily needed by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of fluorinated active pharmaceutical ingredients (APIs), particularly in medicinal chemistry research for drug discovery and development.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides where the fluorine atom enhances stability, bioavailability, and efficacy.
• Organic Synthesis Reagent: Serves as a versatile precursor for further functionalization, including hydrolysis to 2-fluoroaniline or use in palladium-catalyzed cross-coupling reactions.
• Material Science Research: Employed in the development of fluorinated polymers, liquid crystals, and other specialty materials requiring specific electronic properties.
• Dye and Pigment Industry: Acts as an intermediate in the synthesis of complex fluorinated dyes and pigments for high-performance applications.

Basic Information

Product Name	2'-Fluoroacetanilide
CAS No.	399-31-5
Molecular Formula	C8H8FNO
Molecular Weight	153.15 g/mol
Synonyms	N-(2-Fluorophenyl)acetamide; 2-Fluoroacetanilide; 2-Fluoro-N-phenylethanamide; o-Fluoroacetanilide; Acetamide, N-(2-fluorophenyl)-; 2-Fluorophenylacetamide; 1-Acetylamino-2-fluorobenzene; USAF EK-5705
EINECS	206-924-6

Quality Control

Our 2'-Fluoroacetanilide is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity determination and GC/MS, NMR, and IR for identity confirmation, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	96 - 100 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.