Description

3-(2-Fluorophenoxy)-1,2-Propanediol CAS NO 399-28-0 is a versatile fluorinated organic building block characterized by its diol and aryl ether functionalities. This compound is valued for its role as a key intermediate in the synthesis of more complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is primarily sought after by research and development chemists, process development scientists, and manufacturers in fine chemical production. The presence of both reactive hydroxyl groups and a fluorinated aromatic ring makes it a valuable precursor for creating targeted bioactive compounds.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of active pharmaceutical ingredients (APIs), especially for candidates targeting the central nervous system or possessing specific receptor binding profiles.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine atom can enhance biological activity and environmental stability.
• Liquid Crystal & OLED Material Research: Serves as a precursor for fluorinated components in electronic display materials, contributing to improved performance and stability.
• Polymer & Resin Modification: Employed to introduce fluorine and hydroxyl groups into polymer chains, potentially altering surface properties, adhesion, and chemical resistance.
• Organic Synthesis & Catalysis Research: Acts as a model substrate or ligand precursor in methodological development and asymmetric catalysis studies within academic and industrial R&D labs.
• Specialty Chemical Manufacturing: Utilized in the production of custom fluorinated compounds for various high-value industrial applications.

Basic Information

Product Name	3-(2-Fluorophenoxy)-1,2-Propanediol
CAS No.	399-28-0
Molecular Formula	C9H11FO3
Molecular Weight	186.18 g/mol
Synonyms	1,2-Propanediol, 3-(2-fluorophenoxy)-; 3-(2-Fluorophenoxy)propane-1,2-diol; 2-Fluorophenyl glyceryl ether; Glyceryl 2-fluorophenyl ether; 1-Fluoro-2-(2,3-dihydroxypropoxy)benzene; α-(2-Fluorophenoxy)glycerol; 2-Fluorophenoxy-1,2-propanediol
EINECS	Contact for details

Quality Control

Our 3-(2-Fluorophenoxy)-1,2-Propanediol is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, which includes data from HPLC, GC, NMR, and other relevant techniques. Our quality commitment ensures the material meets the stringent requirements for research and GMP-grade manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent moisture absorption. Recommended storage temperature is 2-8°C for extended stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.