Description

2-Ethyl-4-Fluorophenol is a versatile fluorinated phenolic compound that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both an ethyl and a fluorine substituent on the phenol ring, makes it a valuable intermediate for creating complex molecules with tailored properties. This compound is primarily sought after by R&D chemists and process engineers in the pharmaceutical and agrochemical industries for the development of active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring fluorinated aromatic systems for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, where the fluorine atom can improve biological activity and environmental persistence.
• Liquid Crystal Materials: Serves as a precursor in the manufacture of fluorinated compounds for liquid crystal displays (LCDs), contributing to improved dielectric anisotropy and thermal stability.
• Polymer Modification: Acts as a monomer or additive for creating specialty polymers with enhanced chemical resistance, thermal properties, or surface characteristics.
• Organic Electronics: Utilized in the research and development of materials for organic light-emitting diodes (OLEDs) and other electronic applications due to its electron-withdrawing fluorine group.
• Dye and Pigment Intermediate: Employed in the synthesis of complex dyes and pigments, where the fluorine substituent can alter color fastness and solubility properties.

Basic Information

Product Name	2-Ethyl-4-Fluorophenol
CAS No.	398-71-0
Molecular Formula	C8H9FO
Molecular Weight	140.16 g/mol
Synonyms	4-Fluoro-2-ethylphenol; 2-Ethyl-4-fluorophenol; 1-Ethyl-3-fluoro-4-hydroxybenzene; 4-Fluoro-o-ethylphenol; 2-Ethyl-4-fluorohydroxybenzene; Phenol, 2-ethyl-4-fluoro-; 398-71-0; 4-Hydroxy-3-ethylfluorobenzene
EINECS	206-927-5

Quality Control

Our 2-Ethyl-4-Fluorophenol is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to verify identity, potency, and impurity profiles. A Certificate of Analysis (COA) detailing all test results is provided with every shipment. We support cGMP compliance for pharmaceutical applications and can tailor specifications to meet specific customer requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is easily oxidized and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage or when opening containers to prevent degradation. Keep away from strong oxidizing agents, strong bases, and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or crystalline solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.