Description

2,4-Dichloro-7-(Trifluoromethyl)Quinazoline CAS NO 396-02-1 is a high-value halogenated quinazoline derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its core value lies in its bifunctional reactivity, where the chlorine atoms and the quinazoline core enable precise molecular construction for complex target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of novel active ingredients and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of kinase inhibitors, anticancer agents, and other biologically active quinazoline-based compounds.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, leveraging the trifluoromethyl group for enhanced activity and stability.
• Material Science Research: Serves as a precursor for the development of organic electronic materials, dyes, and photoactive compounds.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up processes in fine chemical production.
• Academic & R&D Laboratories: Employed in methodological studies and the discovery of new chemical reactions and catalytic processes.

Basic Information

Product Name	2,4-Dichloro-7-(trifluoromethyl)quinazoline
CAS No.	396-02-1
Molecular Formula	C9H3Cl2F3N2
Molecular Weight	267.04 g/mol
Synonyms	7-(Trifluoromethyl)-2,4-dichloroquinazoline; 2,4-Dichloro-7-trifluoromethylquinazoline; Quinazoline, 2,4-dichloro-7-(trifluoromethyl)-; 2,4-Dichloro-7-(trifluoromethyl)-quinazoline; 2,4-Dichloro-7-trifluoromethyl-quinazoline
EINECS	Contact for details

Quality Control

Our 2,4-Dichloro-7-(trifluoromethyl)quinazoline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and batch-to-batch consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and impurity profiles. We support custom synthesis and purity grades to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Recommended storage temperature is 2-8°C for extended stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.