Description

1-(5-Fluoro-2-Hydroxyphenyl)-1-Ethanone is a versatile fluorinated aromatic ketone building block, valued for its unique molecular structure that combines a phenolic hydroxyl group with an acetyl moiety and a fluorine substituent. This compound is essential for the synthesis of complex molecules, offering chemists a handle for further functionalization and derivatization. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the research and development of advanced herbicides and pesticides, where the fluorine atom enhances biological activity and environmental stability.
• Liquid Crystal & OLED Material Research: Serves as a building block for fluorinated organic electronic materials, contributing to improved performance in display and lighting technologies.
• Organic Synthesis & Chemical Research: A valuable reagent for academic and industrial R&D labs exploring new coupling reactions, heterocycle formation, and complex molecule assembly.
• Dye & Pigment Intermediate: Employed in the development of specialized fluorinated dyes and pigments that offer enhanced lightfastness and unique color properties.

Basic Information

Product Name	1-(5-Fluoro-2-Hydroxyphenyl)-1-Ethanone
CAS No.	394-32-1
Molecular Formula	C8H7FO2
Molecular Weight	154.14 g/mol
Synonyms	5'-Fluoro-2'-hydroxyacetophenone; 2-Acetyl-4-fluorophenol; 1-(5-Fluoro-2-hydroxyphenyl)ethanone; 4-Fluoro-2-hydroxyacetophenone; 2-Hydroxy-5-fluoroacetophenone; 5-Fluoro-2-hydroxyacetophenone; 5-Fluoro-2'-hydroxyacetophenone; 2-Acetyl-4-fluorophenol
EINECS	206-900-7

Quality Control

Our 1-(5-Fluoro-2-Hydroxyphenyl)-1-Ethanone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR, to ensure it meets the high standards required for research and production. Certificates of Analysis (COA) detailing all specifications are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	92 - 96 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.