Description

4-Nitro-3-Trifluoromethyl Aniline is a high-value aromatic amine derivative that serves as a critical building block in advanced chemical synthesis. This compound is prized for its unique combination of electron-withdrawing nitro and trifluoromethyl groups, which impart significant reactivity and stability to target molecules. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting specific receptors or enzymes.
• Agrochemical Synthesis: Used in the production of advanced herbicides, pesticides, and fungicides, leveraging its structural properties for enhanced bioactivity.
• Dye and Pigment Manufacturing: Serves as an intermediate for creating specialized azo dyes and high-performance pigments with improved lightfastness.
• Material Science Research: Employed in the development of novel polymers, liquid crystals, and organic electronic materials due to its aromatic and fluorinated structure.
• Cross-Coupling Reactions: Acts as a valuable substrate in palladium-catalyzed reactions (e.g., Buchwald-Hartwig amination) for constructing complex nitrogen-containing compounds.

Basic Information

Product Name	4-Nitro-3-Trifluoromethyl Aniline
CAS No.	393-11-3
Molecular Formula	C7H5F3N2O2
Molecular Weight	206.12 g/mol
Synonyms	3-(Trifluoromethyl)-4-nitroaniline; 4-Nitro-α,α,α-trifluoro-m-toluidine; 4-Nitro-3-(trifluoromethyl)benzenamine; 1-Amino-2-nitro-5-(trifluoromethyl)benzene; Benzenamine, 4-nitro-3-(trifluoromethyl)-; m-Toluidine, 4-nitro-α,α,α-trifluoro-; 4-Nitro-3-trifluoromethylphenylamine
EINECS	206-884-5

Quality Control

Our 4-Nitro-3-Trifluoromethyl Aniline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by FT-IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber-colored or stored in dark conditions.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	92 - 96 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.