Description

2,2,2-Trifluoro-1-o-Tolyl-Ethylamine is a specialized fluorinated aromatic amine building block of significant interest in advanced organic synthesis. Its core value lies in the unique combination of the electron-withdrawing trifluoromethyl group and the versatile amine functionality, enabling precise modulation of molecular properties. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for creating novel active ingredients, as well as by manufacturers of specialty materials and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine atoms enhance biological activity and environmental stability.
• Ligand & Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of monomers and functional additives for advanced polymers and liquid crystals.
• Fluorine Chemistry Research: A valuable compound for studying structure-activity relationships (SAR) and introducing fluorine into complex molecular architectures.
• Fine Chemical Production: Used in custom synthesis and contract manufacturing for high-value, low-volume specialty chemicals.

Basic Information

Product Name	2,2,2-Trifluoro-1-o-Tolyl-Ethylamine
CAS No.	387-88-2
Molecular Formula	C9H10F3N
Molecular Weight	189.18 g/mol
Synonyms	α-(Trifluoromethyl)-o-tolylmethylamine; 1-(2-Methylphenyl)-2,2,2-trifluoroethylamine; 2,2,2-Trifluoro-1-(2-methylphenyl)ethanamine; o-Methyl-α,α,α-trifluorophenethylamine; 2-Methyl-α-(trifluoromethyl)benzylamine; 1-(2-Methylphenyl)-2,2,2-trifluoroethanamine; (2-Methylphenyl)(trifluoromethyl)methylamine
EINECS	Contact for details

Quality Control

Our 2,2,2-Trifluoro-1-o-Tolyl-Ethylamine is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements of research and industrial synthesis. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available for every shipment upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.