Description

3-Fluoro-2-Nitrophenol is a versatile aromatic intermediate characterized by its distinct fluorine and nitro substituents on the phenol ring. This compound is valued for its role as a key building block in the synthesis of more complex molecules, particularly in the development of advanced agrochemicals and pharmaceuticals. It is primarily sought by R&D chemists and process development teams in the fine chemical, pharmaceutical, and agrochemical industries for constructing active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those requiring fluorinated aromatic structures for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and pesticides, where the fluorine atom can improve biological activity and environmental persistence.
• Dye and Pigment Manufacturing: Acts as an intermediate for synthesizing specialized azo dyes and pigments, contributing to color fastness and specific hue properties.
• Liquid Crystal & OLED Materials: Employed in the research and development of electronic display materials, where its molecular structure can influence electro-optical properties.
• Polymer Modification: Utilized to introduce fluorophenol groups into polymer chains, potentially altering thermal stability, chemical resistance, or surface properties.
• Chemical Research & Development: A valuable reagent for academic and industrial research in organic synthesis, medicinal chemistry, and material science.

Basic Information

Product Name	3-Fluoro-2-Nitrophenol
CAS No.	385-01-3
Molecular Formula	C6H4FNO3
Molecular Weight	157.10 g/mol
Synonyms	2-Nitro-3-fluorophenol; 3-Fluoro-2-nitrophenol; 3-Fluoro-2-hydroxy-nitrobenzene; 2-Hydroxy-6-fluoronitrobenzene; 3-Fluoro-2-nitrophenolate; 3-F-2-NP; Phenol, 3-fluoro-2-nitro-; 1-Fluoro-2-hydroxy-3-nitrobenzene
EINECS	206-851-4

Quality Control

Our 3-Fluoro-2-Nitrophenol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment. We adhere to cGMP principles where applicable to support our customers in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	60 - 64 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.