Description

3,5-Difluoroaniline is a versatile fluorinated aromatic amine building block essential for advanced organic synthesis. Its unique substitution pattern makes it a critical intermediate for creating complex molecules with tailored electronic and steric properties. This compound is primarily used by researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of fluorinated drug candidates.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, where the fluorine atoms enhance biological activity and stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials and organic light-emitting diodes (OLEDs).
• Polymer & Resin Modifier: Incorporated into specialty polymers to improve chemical resistance, thermal stability, and surface properties.
• Dye & Pigment Manufacturing: Intermediate for synthesizing novel fluorinated dyes and pigments with unique color fastness and spectral properties.
• Cross-coupling Reactions: A valuable substrate in palladium-catalyzed reactions (e.g., Buchwald-Hartwig amination, Suzuki coupling) for constructing complex aromatic systems.

Basic Information

Product Name	3,5-Difluoroaniline
CAS No.	372-39-4
Molecular Formula	C6H5F2N
Molecular Weight	129.11 g/mol
Synonyms	3,5-Difluorobenzenamine; 1-Amino-3,5-difluorobenzene; 3,5-Difluorophenylamine; m,m-Difluoroaniline; Benzenamine, 3,5-difluoro-; 3,5-DFA; Aniline, 3,5-difluoro-
EINECS	206-749-5

Quality Control

Our 3,5-Difluoroaniline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong bases and oxidizing agents. Recommended storage temperature is between 15°C and 25°C. The product is light-sensitive and should be stored away from light.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.