Description

4-(Trifluoromethylthio)Aniline is a specialized aromatic amine building block distinguished by the presence of a trifluoromethylthio (-SCF₃) functional group. This unique structure makes it a high-value intermediate for synthesizing advanced molecules with enhanced properties like metabolic stability and lipophilicity. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the -SCF₃ group can improve biological activity and environmental persistence.
• Material Science: Serves as a precursor for functional dyes, liquid crystals, and advanced polymers requiring specific electronic or surface properties.
• Organic Synthesis & Research: A versatile reagent for introducing the trifluoromethylthio moiety into complex organic molecules in academic and industrial R&D settings.

Basic Information

Product Name	4-(Trifluoromethylthio)Aniline
CAS No.	372-16-7
Molecular Formula	C₇H₆F₃NS
Molecular Weight	193.19 g/mol
Synonyms	4-Aminophenyl trifluoromethyl sulfide; p-(Trifluoromethylthio)aniline; 4-(Trifluoromethylsulfanyl)aniline; Benzenamine, 4-[(trifluoromethyl)thio]-; 1-Amino-4-(trifluoromethylthio)benzene; 4-SCF₃-Aniline; p-Aminophenyl trifluoromethyl thioether
EINECS	206-749-5

Quality Control

Our production of 4-(Trifluoromethylthio)Aniline adheres to strict quality management protocols. Each batch undergoes comprehensive analytical testing to ensure high purity and consistency, meeting the stringent requirements of advanced synthetic applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming specifications for identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and acids.

Specification

Item	Specification
Appearance	Light yellow to brown crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.