Description

4-Fluorophenol is a versatile fluorinated aromatic compound that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring a phenolic hydroxyl group and a fluorine atom on the benzene ring, makes it an essential intermediate for creating more complex molecules. This high-purity chemical is primarily utilized by the pharmaceutical, agrochemical, and specialty chemical industries for research, development, and large-scale manufacturing processes.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs containing fluorinated aromatic systems.
• Agrochemical Synthesis: Used in the production of advanced herbicides, pesticides, and fungicides where the fluorine atom enhances biological activity and stability.
• Liquid Crystal Materials: Serves as a building block for fluorinated components in liquid crystal displays (LCDs) and other electronic materials.
• Polymer Chemistry: Employed as a monomer or modifier in the synthesis of specialty polymers, including polyarylates and engineering plastics.
• Organic Synthesis Reagent: Utilized in various coupling reactions, etherifications, and as a protecting group precursor in complex multi-step syntheses.
• Dye and Pigment Manufacturing: Acts as an intermediate for producing fluorinated dyes and pigments with improved properties.

Basic Information

Product Name	4-Fluorophenol
CAS No.	371-41-5
Molecular Formula	C6H5FO
Molecular Weight	112.10 g/mol
Synonyms	p-Fluorophenol; 4-Fluoro-1-hydroxybenzene; 1-Fluoro-4-hydroxybenzene; 4-Hydroxyfluorobenzene; Para-fluorophenol; FPH; UN 1759 (Phenol, molten); Phenol, 4-fluoro-
EINECS	206-730-5

Quality Control

Our 4-Fluorophenol is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive quality assurance, with products typically meeting a purity specification of ≥98.0% (GC) or higher grades upon request. Each batch is accompanied by a detailed Certificate of Analysis (COA) documenting identity, purity, and impurity profiles. Our quality protocols are designed to support applications requiring GMP and ISO standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong oxidizing agents, acids, and bases. Recommended storage temperature is between 15°C and 25°C. Keep container tightly sealed when not in use to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Melting Point	46°C - 50°C
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.