Description

4-Fluoroaniline is a versatile fluorinated aromatic amine, serving as a critical building block in advanced organic synthesis. Its value lies in the introduction of both an amine and a fluorine substituent onto a benzene ring, enabling the creation of complex molecules with tailored properties. This intermediate is essential for manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediates: Key precursor in the synthesis of fluoroquinolone antibiotics, antidepressant agents, and other active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the production of herbicides, pesticides, and fungicides, where the fluorine atom enhances biological activity and stability.
• Dye and Pigment Manufacturing: Serves as a starting material for azo dyes and other colorants, contributing to lightfastness and color intensity.
• Liquid Crystal & Electronic Materials: A building block for fluorinated compounds used in liquid crystal displays (LCDs) and organic light-emitting diodes (OLEDs).
• Polymer Modification: Employed to introduce fluorinated aniline units into polymer chains, altering surface properties and chemical resistance.
• Cross-Coupling Reactions: A valuable substrate in Buchwald-Hartwig amination and other palladium-catalyzed reactions for creating complex aryl amines.

Basic Information

Product Name	4-Fluoroaniline
CAS No.	371-40-4
Molecular Formula	C6H6FN
Molecular Weight	111.12 g/mol
Synonyms	p-Fluoroaniline; 4-Fluoroaniline; 4-Fluoro-benzenamine; 1-Amino-4-fluorobenzene; p-Fluorophenylamine; 4-FA; FAN; 4-Fluorobenzenamine; UN 2941
EINECS	206-731-2

Quality Control

Our 4-Fluoroaniline is produced under stringent quality management systems. Every batch undergoes comprehensive analytical testing, including Gas Chromatography (GC) and HPLC, to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C) under an inert atmosphere (e.g., nitrogen) to minimize oxidation. Keep away from heat, open flames, and incompatible materials such as strong oxidizing agents and acids.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms
Assay (GC)	≥ 99.0%
Water Content (KF)	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 0.5%
Density (20°C)	~1.17 g/cm³
Boiling Point	~187-188°C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.