Description

2-(3,5-Difluorophenoxy)Acetic Acid is a high-purity fluorinated aromatic building block of significant importance in advanced organic synthesis. Its core value lies in its role as a versatile intermediate for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and agrochemicals. This compound is essential for research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to incorporate difluorophenoxy motifs into their target structures.

Application

• Pharmaceutical Intermediate: A key synthon in the research and production of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, anti-inflammatory agents, and oncology therapeutics.
• Agrochemical Synthesis: Used in the manufacture of advanced herbicides, fungicides, and plant growth regulators where the difluorophenoxy group enhances biological activity and environmental stability.
• Liquid Crystal & OLED Material Precursor: Serves as a building block for fluorinated aromatic components in electronic display materials and organic light-emitting diodes (OLEDs).
• Polymer Modification: Employed to introduce fluorinated side chains into polymers, altering properties such as hydrophobicity, chemical resistance, and thermal stability.
• Chemical Research & Development: A valuable reagent for academic and industrial R&D in organic chemistry, facilitating the study of structure-activity relationships (SAR).
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific target molecules.

Basic Information

Product Name	2-(3,5-Difluorophenoxy)Acetic Acid
CAS No.	370-02-5
Molecular Formula	C8H6F2O3
Molecular Weight	188.13 g/mol
Synonyms	(3,5-Difluorophenoxy)acetic Acid; Acetic Acid, 2-(3,5-difluorophenoxy)-; 3,5-Difluorophenoxyacetic Acid; 2-(3,5-Difluorophenoxy)ethanoic Acid; NSC 406106; DFPA; Difluorophenoxyacetic Acid
EINECS	206-729-1

Quality Control

Our 2-(3,5-Difluorophenoxy)Acetic Acid is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets exacting specifications for research and commercial use. A Certificate of Analysis (COA) detailing all test results is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	118°C - 122°C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.