Description

3-(Trifluoromethylthio)Aniline is a versatile fluorinated aromatic amine building block characterized by its unique trifluoromethylthio (-SCF₃) functional group. This compound is highly valued in advanced organic synthesis for introducing lipophilic and electron-withdrawing properties into target molecules. It serves as a critical intermediate for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of drugs targeting central nervous system (CNS) disorders, anti-infectives, and oncology therapeutics.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the trifluoromethylthio group enhances biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor in the manufacture of fluorinated components for electronic displays and organic light-emitting diodes (OLEDs), improving charge transport and device performance.
• Polymer & Resin Modifier: Incorporated into specialty polymers and epoxy resins to impart enhanced chemical resistance, thermal stability, and surface properties.
• Dye & Pigment Intermediate: Utilized in the synthesis of high-performance, light-fast dyes and pigments for specialized industrial applications.
• Chemical Research & Development: An essential reagent in academic and industrial R&D for exploring new reactions, catalytic processes, and material science applications.

Basic Information

Product Name	3-(Trifluoromethylthio)Aniline
CAS No.	369-68-6
Molecular Formula	C₇H₆F₃NS
Molecular Weight	193.19 g/mol
Synonyms	3-(Trifluoromethylthio)benzenamine; 3-Aminophenyl trifluoromethyl sulfide; m-(Trifluoromethylthio)aniline; 3-(Trifluoromethylsulfanyl)aniline; Benzenamine, 3-[(trifluoromethyl)thio]-; 3-SCF₃-Aniline; α,α,α-Trifluoro-m-toluidine thioether
EINECS	206-732-5

Quality Control

Our production of 3-(Trifluoromethylthio)Aniline adheres to a strict quality management system to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to verify identity, potency, and impurity profiles. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Light yellow to brown crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.