Description

2-Fluoro-4-Nitroaniline is a high-purity, light-sensitive aromatic amine derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the strategic positioning of its functional groups, which enable precise chemical modifications for creating complex molecular architectures. This intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds containing fluorinated aniline motifs.
• Agrochemical Synthesis: Used in the development of advanced herbicides, pesticides, and fungicides where the fluorine and nitro groups confer specific biological activity and stability.
• Dye and Pigment Manufacturing: Serves as a starting material for producing azo dyes and other complex colorants, contributing to color fastness and specific hue properties.
• Organic Light-Emitting Diodes (OLEDs): Acts as a building block for electron-transport materials or host materials in OLED device fabrication.
• Liquid Crystal (LC) Materials: Utilized in the synthesis of fluorinated components for liquid crystal mixtures used in displays.
• Cross-Coupling Reactions: The aniline and halogen functionalities make it a valuable substrate in palladium-catalyzed cross-coupling reactions (e.g., Buchwald-Hartwig amination).
• Research & Development: A versatile reagent in academic and industrial R&D for exploring new synthetic pathways and creating novel chemical entities.

Basic Information

Product Name	2-Fluoro-4-Nitroaniline
CAS No.	369-35-7
Molecular Formula	C6H5FN2O2
Molecular Weight	156.11 g/mol
Synonyms	4-Nitro-2-fluoroaniline; 2-Fluoro-4-nitrobenzenamine; 1-Amino-2-fluoro-4-nitrobenzene; 2-Fluoro-4-nitro-phenylamine; 4-Nitro-2-fluoro-phenylamine; 2-FA-4-NA; FNA
EINECS	206-719-5

Quality Control

Our 2-Fluoro-4-Nitroaniline is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency meet the stringent requirements of our global B2B clients. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting all critical quality parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber-colored or stored in light-resistant secondary packaging.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	92 - 96 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.