Description

3-(Difluoromethyl)Aniline is a versatile fluorinated aromatic amine building block, prized for its unique chemical reactivity and the introduction of the difluoromethyl group. This compound is essential for the synthesis of advanced agrochemicals and pharmaceuticals, where its structural motif can significantly enhance biological activity and metabolic stability. It serves as a critical intermediate for researchers and manufacturers in the fine chemical, crop protection, and pharmaceutical development sectors.

Application

• Agrochemical Intermediate: Key precursor in the synthesis of novel fungicides, herbicides, and insecticides, leveraging the difluoromethyl group for improved efficacy and environmental profile.
• Pharmaceutical Building Block: Used in medicinal chemistry for the development of active pharmaceutical ingredients (APIs), particularly in molecules targeting metabolic and central nervous system disorders.
• Material Science Research: Employed in the creation of specialty polymers, liquid crystals, and advanced organic electronic materials due to its aromatic and fluorine-containing properties.
• Dye and Pigment Synthesis: Serves as an intermediate for producing specialized dyes and colorants with enhanced lightfastness and chemical resistance.
• Cross-Coupling Reactions: A valuable substrate in palladium-catalyzed reactions (e.g., Buchwald-Hartwig amination) for constructing complex nitrogen-containing compounds.

Basic Information

Product Name	3-(Difluoromethyl)Aniline
CAS No.	368-99-0
Molecular Formula	C7H7F2N
Molecular Weight	143.13 g/mol
Synonyms	3-(Difluoromethyl)benzenamine; m-(Difluoromethyl)aniline; 3-Aminobenzylidene difluoride; Benzenamine, 3-(difluoromethyl)-; α,α-Difluoro-m-toluidine; 1-Amino-3-(difluoromethyl)benzene; 3-(Difluoromethyl)phenylamine
EINECS	Contact for details

Quality Control

Our production of 3-(Difluoromethyl)Aniline adheres to a stringent quality management system to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques including GC, HPLC, and NMR to verify identity, potency, and impurity profiles. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment, ensuring full traceability and compliance with your research or manufacturing requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during storage.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC/HPLC)	≤ 2.0% total

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.