Description

Acetamide, n-[2-Hydroxy-5-(Trifluoromethyl)Phenyl]- is a specialized trifluoromethyl-substituted aromatic amide compound, identified by CAS number 368-11-6. This high-purity intermediate is valued for its unique molecular structure, which combines a phenolic hydroxyl group with a robust trifluoromethyl moiety, offering distinct reactivity and physicochemical properties. It is primarily sought by research and development chemists in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of new drug candidates, particularly for molecules requiring the metabolic stability and lipophilicity imparted by the trifluoromethyl group.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides where the specific substitution pattern can enhance biological activity and environmental profile.
• Liquid Crystal & OLED Material Research: Serves as a precursor or dopant in the development of specialty electronic materials for displays and lighting applications.
• Organic Synthesis & Catalysis: Employed as a versatile reagent or ligand scaffold in complex organic transformations and catalytic processes within fine chemical manufacturing.
• Academic & Industrial R&D: A critical compound for methodological studies and exploratory chemistry in universities and corporate research laboratories worldwide.

Basic Information

Product Name	Acetamide, n-[2-Hydroxy-5-(Trifluoromethyl)Phenyl]-
CAS No.	368-11-6
Molecular Formula	C9H8F3NO2
Molecular Weight	219.16 g/mol
Synonyms	N-[2-Hydroxy-5-(trifluoromethyl)phenyl]acetamide; 2'-Hydroxy-5'-(trifluoromethyl)acetanilide; 5-(Trifluoromethyl)-2-acetamidophenol; 2-Acetamido-5-(trifluoromethyl)phenol; Acetamide, N-[2-hydroxy-5-(trifluoromethyl)phenyl]-; 368-11-6; N-(2-Hydroxy-5-trifluoromethylphenyl)acetamide
EINECS	Contact for details

Quality Control

Our Acetamide, n-[2-Hydroxy-5-(Trifluoromethyl)Phenyl]- is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and moisture. We provide a detailed Certificate of Analysis (COA) with each shipment to ensure traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.