Description

2,4-Difluoroaniline is a versatile halogenated aromatic amine, serving as a critical building block in advanced organic synthesis. Its value lies in the strategic positioning of fluorine atoms on the aniline ring, which significantly influences the electronic properties and metabolic stability of final compounds. This intermediate is essential for manufacturers in the pharmaceutical and agrochemical sectors, where it is used to create active ingredients with enhanced efficacy and specificity.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting central nervous system disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Building block for manufacturing advanced herbicides, fungicides, and pesticides, where the fluorine atoms contribute to improved biological activity and environmental profile.
• Liquid Crystal & OLED Materials: Used in the production of fluorine-containing compounds for electronic display materials, contributing to stability and performance.
• Dye and Pigment Manufacturing: Intermediate for creating specialized, light-fast azo dyes and high-performance pigments.
• Polymer Modification: Serves as a monomer or additive to introduce fluorine into polymer chains, enhancing material properties like chemical resistance and thermal stability.
• Research & Development: Valuable reagent in academic and industrial R&D for exploring new fluorinated compounds and reaction pathways.

Basic Information

Product Name	2,4-Difluoroaniline
CAS No.	367-25-9
Molecular Formula	C6H5F2N
Molecular Weight	129.11 g/mol
Synonyms	2,4-DFA; 1-Amino-2,4-difluorobenzene; 2,4-Difluorobenzenamine; 2,4-Difluorophenylamine; 2,4-Difluoroaniline; 2,4-Difluoro-1-aminobenzene; Aniline, 2,4-difluoro-
EINECS	206-695-8

Quality Control

Our 2,4-Difluoroaniline is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including GC/HPLC for purity and identity confirmation, to ensure it meets the high standards required for fine chemical synthesis. Certificates of Analysis (COA) detailing all specifications are provided with each shipment. We adhere to cGMP principles where applicable to support our customers in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong bases and oxidizing agents. Recommended storage temperature is between 15°C and 25°C. The container must be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.5%
Water Content (KF)	≤ 0.5%
Related Substances (GC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%
Density (at 20°C)	~1.26 g/cm³
Boiling Point	~169-171 °C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.