Description

3'-Trifluoromethylbiphenyl-2-Ylamine is a high-purity aromatic amine building block characterized by its biphenyl core and strategically positioned trifluoromethyl and amine functional groups. This compound is valued for its role in modulating the physicochemical properties of advanced materials and active pharmaceutical ingredients, particularly through the introduction of lipophilicity and metabolic stability. It is primarily sought by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for the synthesis of novel compounds and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of active pharmaceutical ingredients (APIs), especially for candidates targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a core structure in the development of organic electronic materials, including charge-transport layers and emissive materials for displays.
• Polymer & Resin Modifier: Incorporated into specialty polymers to improve thermal stability, chemical resistance, and optical properties.
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and as a precursor for heterocyclic compounds in academic and industrial research.
• Dye & Pigment Manufacturing: Acts as an intermediate in the synthesis of complex organic dyes and pigments with specific color fastness and solubility profiles.

Basic Information

Product Name	3'-Trifluoromethylbiphenyl-2-Ylamine
CAS No.	365-06-0
Molecular Formula	C13H10F3N
Molecular Weight	237.22 g/mol
Synonyms	2-Amino-3'-(trifluoromethyl)biphenyl; [1,1'-Biphenyl]-2-amine, 3'-(trifluoromethyl)-; 3'-(Trifluoromethyl)[1,1'-biphenyl]-2-amine; 2-Amino-3'-trifluoromethylbiphenyl; 3'-Trifluoromethyl-2-biphenylamine; 2-Biphenylamine, 3'-trifluoromethyl-; 3'-Trifluoromethylbiphenyl-2-amine; 3-(Trifluoromethyl)biphenyl-2-ylamine
EINECS	Contact for details

Quality Control

Our 3'-Trifluoromethylbiphenyl-2-Ylamine is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive and should be stored away from light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.