Description

4-Fluoro-3-Nitroaniline is a high-purity aromatic amine derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both an electron-withdrawing nitro group and an electron-donating amino group on a fluorinated benzene ring, makes it an indispensable intermediate for creating complex molecules. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly in the development of fluorinated heterocycles and active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and fungicides where the fluorine atom enhances biological activity and environmental stability.
• Dye and Pigment Manufacturing: Serves as a starting material for synthesizing specialized azo dyes and pigments, contributing to color fastness and unique spectral properties.
• Material Science Research: Employed in the development of organic semiconductors, liquid crystals, and polymers where fluorinated aromatic amines modify electronic and physical properties.
• Cross-Coupling Reactions: Valuable substrate in palladium-catalyzed reactions (e.g., Buchwald-Hartwig amination) for constructing complex nitrogen-containing architectures.

Basic Information

Product Name	4-Fluoro-3-Nitroaniline
CAS No.	364-76-1
Molecular Formula	C6H5FN2O2
Molecular Weight	156.11 g/mol
Synonyms	3-Nitro-4-fluoroaniline; 4-Fluoro-3-nitrobenzenamine; 1-Amino-4-fluoro-3-nitrobenzene; 4-Fluoro-3-nitro-phenylamine; 4-F-A-3-NO2; FNA; 4-F-3-NO2-Aniline; 3-Nitro-4-fluoroaniline
EINECS	206-669-1

Quality Control

Our 4-Fluoro-3-Nitroaniline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets the stringent requirements of our global clientele. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids, strong bases, and oxidizing agents. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	94 - 98 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.