Description

4-Fluoro-2-Nitroaniline is a versatile aromatic amine derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both an electron-withdrawing nitro group and a fluorine atom, makes it a valuable intermediate for creating complex molecules with specific electronic and steric properties. This compound is essential for research and production in the pharmaceutical and agrochemical industries, where it is used to develop active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for fluorinated compounds and heterocyclic systems.
• Agrochemical Synthesis: Used in the manufacture of advanced herbicides, pesticides, and fungicides, leveraging the fluorine atom for enhanced bioactivity and stability.
• Dye and Pigment Manufacturing: Serves as a starting material for producing azo dyes and other complex colorants, where the nitro and amino groups facilitate chromophore formation.
• Material Science Research: Employed in the development of organic electronic materials, liquid crystals, and polymers that require fluorinated aniline derivatives.
• Chemical Research & Development: A valuable reagent for academic and industrial R&D focused on nucleophilic aromatic substitution and palladium-catalyzed cross-coupling reactions.

Basic Information

Product Name	4-Fluoro-2-Nitroaniline
CAS No.	364-71-6
Molecular Formula	C6H5FN2O2
Molecular Weight	156.11 g/mol
Synonyms	2-Nitro-4-fluoroaniline; 4-Fluoro-2-nitrobenzenamine; 1-Amino-4-fluoro-2-nitrobenzene; 4-Fluoro-2-nitro-phenylamine; Benzenamine, 4-fluoro-2-nitro-; 4-Fluoro-2-nitroaniline; 2-Nitro-4-fluoroaniline
EINECS	206-667-5

Quality Control

Our 4-Fluoro-2-Nitroaniline is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support cGMP and ISO standards for industrial and research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, the container should be opaque or stored in darkness.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	92 - 96 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.