Description

2,4-Difluoro-6-Nitrophenol is a versatile fluorinated aromatic intermediate of significant importance in advanced organic synthesis. Its unique structure, featuring both electron-withdrawing nitro and fluoro substituents, makes it a valuable building block for creating complex molecules with tailored properties. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring fluorinated aromatic cores to modulate bioavailability and metabolic stability.
• Agrochemical Synthesis: Used in the development of novel herbicides, pesticides, and fungicides, where the difluoro-nitrophenol moiety can contribute to biological activity and environmental persistence profiles.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorinated components in electronic display materials, enhancing thermal stability and optical properties.
• Polymer & Resin Modifier: Incorporated into specialty polymers to impart specific characteristics such as chemical resistance, thermal stability, or unique reactivity.
• Dye & Pigment Intermediate: Utilized in the production of specialized dyes and pigments where fluorine atoms can alter color fastness and solubility.
• Research & Development: A valuable reagent in academic and industrial R&D for exploring new synthetic pathways and creating novel fluorinated compounds.

Basic Information

Product Name	2,4-Difluoro-6-Nitrophenol
CAS No.	364-31-8
Molecular Formula	C6H3F2NO3
Molecular Weight	175.09 g/mol
Synonyms	2,4-Difluoro-6-nitrophenol; 6-Nitro-2,4-difluorophenol; 2,4-Difluoro-6-nitro-1-phenol; Phenol, 2,4-difluoro-6-nitro-; 1-Hydroxy-2,4-difluoro-6-nitrobenzene; 2,4-Difluoro-6-hydroxy-nitrobenzene; NSC 406106
EINECS	Contact for details

Quality Control

Our 2,4-Difluoro-6-Nitrophenol is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and purity determination, to meet the stringent requirements of our industrial and research partners. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability and compliance with your quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases, reducing agents, and sources of ignition. Due to its phenolic and nitro-functional groups, it should be handled with appropriate personal protective equipment in accordance with safety data sheet guidelines.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.