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3-Fluoro-4-Methoxybenzyl Chloride CAS NO 351-52-0


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CAS No.:351-52-0

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

3-Fluoro-4-Methoxybenzyl Chloride is a versatile and reactive benzyl chloride derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the strategic positioning of the fluorine and methoxy substituents, which allows for precise functionalization and the creation of complex molecular architectures. This intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries, where it is used to develop active ingredients and novel materials.

Application

  • Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a fluorinated benzyl moiety.
  • Agrochemical Synthesis: Building block for developing advanced herbicides, fungicides, and insecticides, where the fluorine atom enhances biological activity and stability.
  • Liquid Crystal & OLED Materials: Used in the production of fluorinated aromatic compounds for electronic display technologies.
  • Functional Polymer Monomer: Serves as a monomer or cross-linking agent for creating specialty polymers with tailored properties.
  • Organic Synthesis Reagent: Employed in nucleophilic substitution reactions to introduce the 3-fluoro-4-methoxybenzyl group into target molecules.
  • Dye & Pigment Intermediate: Used in the manufacture of complex dyes and pigments for high-performance applications.

Basic Information

Product Name 3-Fluoro-4-Methoxybenzyl Chloride
CAS No. 351-52-0
Molecular Formula C8H8ClFO
Molecular Weight 174.60 g/mol
Synonyms 1-(Chloromethyl)-3-fluoro-4-methoxybenzene; 3-Fluoro-4-methoxybenzyl chloride; 4-Methoxy-3-fluorobenzyl chloride; (3-Fluoro-4-methoxyphenyl)methyl chloride; α-Chloro-3-fluoro-4-methoxytoluene; 3-Fluoro-p-anisyl chloride; 3-Fluoro-4-methoxybenzylchloride; 3-Fluoro-4-methoxybenzyl chloride (351-52-0)
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Quality Control

Our 3-Fluoro-4-Methoxybenzyl Chloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent decomposition. Keep away from strong acids and organic solvents.

Specification

Item Specification
Appearance Colorless to pale yellow liquid
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 98.0%
Water Content (KF) ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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