Description

N-(Chloroacetyl)-4-Fluoroaniline is a high-purity fluorinated aniline derivative, serving as a critical building block in advanced organic synthesis. Its molecular structure, featuring both a reactive chloroacetyl group and a fluoro-substituted aromatic ring, makes it an essential intermediate for creating complex molecules with targeted properties. This compound is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical industries for the development of new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the development of advanced herbicides and pesticides, where the fluorine atom enhances biological activity and environmental stability.
• Material Science Research: Serves as a monomer or modifying agent in the creation of specialty polymers and liquid crystals.
• Dye and Pigment Manufacturing: Intermediate for producing fluorinated dyes that offer improved lightfastness and color properties.
• Organic Light-Emitting Diode (OLED) Materials: Building block for electron-transport or host materials in OLED device fabrication.
• Cross-Coupling Reactions: Valuable substrate in palladium-catalyzed reactions (e.g., Suzuki, Buchwald-Hartwig) for constructing biaryl structures.

Basic Information

Product Name	N-(Chloroacetyl)-4-Fluoroaniline
CAS No.	351-04-2
Molecular Formula	C8H7ClFNO
Molecular Weight	187.60 g/mol
Synonyms	4'-Fluoro-2-chloroacetanilide; 2-Chloro-N-(4-fluorophenyl)acetamide; N-(4-Fluorophenyl)chloroacetamide; 4-Fluoroacetanilide, N-chloroacetyl-; 2-Chloroacet-4'-fluoroanilide; p-Fluoro-N-chloroacetylaniline; Chloroacetyl-4-fluoroaniline; 351-04-2
EINECS	206-506-5

Quality Control

Our N-(Chloroacetyl)-4-Fluoroaniline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistent quality for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Melting Point	108°C - 112°C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.