Description

4-(Trifluoromethyl)Benzyl Alcohol is a versatile fluorinated aromatic alcohol, serving as a critical building block in advanced organic synthesis. Its value lies in the unique combination of the benzyl alcohol moiety and the electron-withdrawing trifluoromethyl group, which imparts desirable properties like enhanced lipophilicity and metabolic stability to final compounds. This compound is essential for research and production in the pharmaceutical, agrochemical, and specialty materials industries, where it is used to create active ingredients and functional intermediates.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting central nervous system disorders, inflammation, and infectious diseases.
• Agrochemical Synthesis: Building block for developing novel herbicides, fungicides, and insecticides, leveraging the trifluoromethyl group to improve biological activity and environmental profile.
• Liquid Crystal & OLED Materials: Used in the production of fluorinated components for electronic displays and organic light-emitting diodes due to its influence on molecular polarity and stability.
• Polymer & Resin Modification: Acts as a monomer or cross-linking agent to introduce fluorine into polymers, enhancing chemical resistance, thermal stability, and surface properties.
• Organic Synthesis Reagent: Employed in various reactions, including esterifications, etherifications, and as a protecting group, in fine chemical and academic research laboratories.
• Dye & Pigment Manufacturing: Intermediate for synthesizing specialty dyes and pigments where the CF₃ group alters color fastness and solubility characteristics.

Basic Information

Product Name	4-(Trifluoromethyl)Benzyl Alcohol
CAS No.	349-95-1
Molecular Formula	C₈H₇F₃O
Molecular Weight	176.14 g/mol
Synonyms	α-(Trifluoromethyl)-p-tolyl alcohol; (4-(Trifluoromethyl)phenyl)methanol; p-(Trifluoromethyl)benzyl alcohol; 4-(Trifluoromethyl)benzenemethanol; 1-(Trifluoromethyl)-4-(hydroxymethyl)benzene; NSC 404080; α,α,α-Trifluoro-p-tolyl alcohol
EINECS	206-498-6

Quality Control

Our 4-(Trifluoromethyl)Benzyl Alcohol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment. We support compliance with global regulatory frameworks, including REACH, and can tailor specifications to meet pharmaceutical (GMP), agrochemical, or research-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible materials such as oxidizing agents. The product is light-sensitive (store away from light) and should be handled in accordance with good laboratory practices to maintain stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or crystalline solid
Identification (IR)	Conforms to structure
Assay (HPLC/GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.