Description

2-Methoxy-5-(Trifluoromethyl)Aniline is a versatile aromatic amine derivative distinguished by its methoxy and trifluoromethyl substituents. This compound is a critical building block in advanced organic synthesis, valued for its electron-withdrawing trifluoromethyl group which imparts unique chemical and physical properties to target molecules. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting central nervous system disorders and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a building block for electron-transport materials and charge-transporting layers in electronic displays and optoelectronic devices.
• Dye & Pigment Manufacturing: Employed in the synthesis of high-performance, light-fast dyes and organic pigments for industrial applications.
• Polymer Chemistry: Acts as a monomer or functionalizing agent for creating specialty polymers with tailored thermal and chemical resistance properties.
• Research & Development: Utilized in academic and industrial R&D labs for exploring novel chemical reactions and developing new synthetic methodologies.

Basic Information

Product Name	2-Methoxy-5-(Trifluoromethyl)Aniline
CAS No.	349-65-5
Molecular Formula	C8H8F3NO
Molecular Weight	191.15 g/mol
Synonyms	5-(Trifluoromethyl)-2-methoxyaniline; 2-Methoxy-α,α,α-trifluoro-p-toluidine; 2-Amino-5-methoxybenzotrifluoride; 5-Amino-2-methoxybenzotrifluoride; 2-Methoxy-5-trifluoromethylaniline; 2-Methoxy-5-(trifluoromethyl)benzenamine; 5-Trifluoromethyl-2-methoxyaniline; 2-Methoxy-α,α,α-trifluoro-p-toluidine
EINECS	206-497-6

Quality Control

Our 2-Methoxy-5-(Trifluoromethyl)Aniline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment aligns with cGMP principles where applicable, ensuring reliability for your critical synthesis processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flames. Due to its light-sensitive nature, the container should be amber-colored or stored in a dark place.

Specification

Item	Specification
Appearance	Light yellow to brown crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	40 - 44 °C
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.