Description

3-Methoxy-5-(Trifluoromethyl)Phenol is a versatile fluorinated phenolic compound, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both a methoxy group and a trifluoromethyl substituent on the aromatic ring, makes it a valuable intermediate for creating molecules with enhanced properties. This compound is particularly sought after by the pharmaceutical and agrochemical industries for the development of active ingredients, where the trifluoromethyl group is known to improve metabolic stability and bioavailability. Its utility extends to materials science for the synthesis of specialty polymers and functional materials.

Application

• Pharmaceutical Intermediate: Key synthon for the development of active pharmaceutical ingredients (APIs), especially in antiviral, anti-inflammatory, and central nervous system (CNS) drug candidates.
• Agrochemical Synthesis: Used in the manufacture of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorine-containing monomers and charge-transport materials used in display technologies and organic light-emitting diodes.
• Polymer Modification: Incorporated as a functional monomer to impart specific characteristics like chemical resistance, thermal stability, or altered surface properties to specialty polymers.
• Dye & Pigment Intermediate: Utilized in the synthesis of complex, high-performance dyes and pigments for specialized applications.
• Chemical Research & Development: A valuable reagent in academic and industrial R&D for exploring new synthetic pathways and fluorine chemistry.

Basic Information

Product Name	3-Methoxy-5-(Trifluoromethyl)Phenol
CAS No.	349-56-4
Molecular Formula	C8H7F3O2
Molecular Weight	192.14 g/mol
Synonyms	5-(Trifluoromethyl)-3-methoxyphenol; 3-Methoxy-α,α,α-trifluoro-m-cresol; 3-Hydroxy-5-methoxybenzotrifluoride; m-Methoxy-α,α,α-trifluorophenol; 3-Methoxy-5-trifluoromethylphenol; 349-56-4; Phenol, 3-methoxy-5-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our production of 3-Methoxy-5-(Trifluoromethyl)Phenol adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including chromatographic purity assays and identity confirmation. Certificates of Analysis (COA) detailing specific test results are provided with every shipment. We support compliance with global regulatory frameworks, including REACH, and can tailor specifications to meet GMP or other specific customer requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and sources of ignition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.