Description

5-Chloro-2,4-Difluoroaniline is a halogenated aniline derivative that serves as a critical building block in advanced organic synthesis. Its unique substitution pattern makes it a valuable intermediate for creating complex molecules with tailored properties. This compound is primarily utilized by the pharmaceutical and agrochemical industries for the development of active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs containing difluorophenyl or chlorophenyl motifs.
• Agrochemical Synthesis: Used in the manufacture of advanced herbicides, fungicides, and pesticides, where the chloro and fluoro substituents enhance biological activity.
• Liquid Crystal & OLED Materials: Serves as a starting material for synthesizing fluorinated aromatic compounds used in electronic displays and organic light-emitting diodes.
• Dye & Pigment Manufacturing: Intermediate for producing specialized azo dyes and high-performance pigments requiring halogenated aniline components.
• Polymer Chemistry: Building block for monomers and additives that impart specific properties like flame retardancy or chemical resistance to polymers.
• Research & Development: Essential reagent in academic and industrial R&D for exploring new chemical entities and reaction pathways.

Basic Information

Product Name	5-Chloro-2,4-Difluoroaniline
CAS No.	348-65-2
Molecular Formula	C6H4ClF2N
Molecular Weight	163.55 g/mol
Synonyms	2,4-Difluoro-5-chloroaniline; 5-Chloro-2,4-difluorobenzenamine; 1-Amino-5-chloro-2,4-difluorobenzene; Benzenamine, 5-chloro-2,4-difluoro-; 5-Chloro-2,4-difluoro-phenylamine; 348-65-2; 5-Chloro-2,4-DFA
EINECS	206-485-8

Quality Control

Our 5-Chloro-2,4-Difluoroaniline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee compliance with your specifications and industry standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials such as strong oxidizing agents and acids. The compound is light-sensitive and should be handled accordingly.

Specification

Item	Specification
Appearance	White to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	40 - 44 °C
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.