Description

4-Chloro-3-Fluorophenol is a versatile halogenated phenol derivative that serves as a critical building block in advanced organic synthesis. Its unique substitution pattern makes it a valuable intermediate for creating complex molecules with tailored properties. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to develop active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring halogenated aromatic scaffolds.
• Agrochemical Synthesis: Building block for manufacturing herbicides, fungicides, and pesticides, leveraging its phenolic and halogen functionalities.
• Liquid Crystal & Polymer Chemistry: Used in the production of specialty monomers and polymers for electronic displays and high-performance materials.
• Dyestuff & Pigment Manufacturing: Intermediate for creating halogenated dyes and organic pigments with specific color fastness and stability.
• Organic Synthesis Reagent: Employed in cross-coupling reactions, etherification, and as a protecting group precursor in complex multi-step syntheses.

Basic Information

Product Name	4-Chloro-3-Fluorophenol
CAS No.	348-60-7
Molecular Formula	C6H4ClFO
Molecular Weight	146.55 g/mol
Synonyms	3-Fluoro-4-chlorophenol; 4-Chloro-3-fluorophenol; Phenol, 4-chloro-3-fluoro-; 1-Chloro-2-fluoro-4-hydroxybenzene; 2-Fluoro-4-hydroxy-1-chlorobenzene; 4-Chloro-3-fluoro-1-hydroxybenzene; FC6P; 348-60-7
EINECS	206-488-6

Quality Control

Our 4-Chloro-3-Fluorophenol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatography and spectroscopy, to ensure it meets high-purity standards suitable for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be opaque or stored in dark conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	44 - 48 °C
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.