Description

Ethyl 5-Fluoroindole-2-Carboxylate is a high-purity fluorinated indole derivative, serving as a critical building block in advanced organic synthesis. Its value lies in providing a versatile scaffold for constructing complex molecules with tailored biological and material properties. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to incorporate the 5-fluoroindole motif into new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Used to develop new herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Material Science: Serves as a monomer or functional unit in the creation of advanced polymers, liquid crystals, and organic electronic materials.
• Chemical Biology: Employed as a probe or labeling reagent in biochemical assays and diagnostic development.
• Academic & Contract Research: A valuable reagent for methodological studies in organic chemistry and medicinal chemistry programs.

Basic Information

Product Name	Ethyl 5-Fluoroindole-2-Carboxylate
CAS No.	348-36-7
Molecular Formula	C11H10FNO2
Molecular Weight	207.20 g/mol
Synonyms	5-Fluoro-1H-indole-2-carboxylic acid ethyl ester; Ethyl 5-fluoro-1H-indole-2-carboxylate; 5-Fluoroindole-2-carboxylic acid ethyl ester; 2-Carbethoxy-5-fluoroindole; 5-Fluoro-2-indolecarboxylic acid ethyl ester; 1H-Indole-2-carboxylic acid, 5-fluoro-, ethyl ester; Ethyl 5-fluoroindole-2-carboxylate
EINECS	Contact for details

Quality Control

Our Ethyl 5-Fluoroindole-2-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specifications and test results. Our commitment to quality supports compliance with cGMP and ISO standards for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.