Description

Ethyl-4-Fluoroindole-2-Carboxylate is a high-value fluorinated indole derivative, a crucial synthetic intermediate in modern organic chemistry. Its core value lies in its role as a versatile building block for constructing complex molecules with tailored biological and physical properties. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and advanced materials sectors.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and inflammation.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides, where the fluorine atom can enhance metabolic stability and bioactivity.
• Material Science: Serves as a monomer or functional component in the creation of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Biology: Employed as a probe or labeled compound in biochemical assays and diagnostic research due to its fluorinated structure.
• Academic & Contract Research: A fundamental reagent for method development and exploratory synthesis in university and CRO (Contract Research Organization) laboratories.

Basic Information

Product Name	Ethyl-4-Fluoroindole-2-Carboxylate
CAS No.	348-32-3
Molecular Formula	C11H10FNO2
Molecular Weight	207.20 g/mol
Synonyms	Ethyl 4-Fluoro-1H-indole-2-carboxylate; 4-Fluoroindole-2-carboxylic Acid Ethyl Ester; 1H-Indole-2-carboxylic acid, 4-fluoro-, ethyl ester; Ethyl 4-fluoroindole-2-carboxylate; 2-Carbethoxy-4-fluoroindole; 4-Fluoro-1H-indole-2-carboxylic acid ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl-4-Fluoroindole-2-Carboxylate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Custom synthesis and purification to meet specific research or cGMP guidelines are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.