Description

2-Fluoro-4-Hydroxybenzaldehyde is a versatile fluorinated aromatic aldehyde, serving as a critical building block in advanced organic synthesis. Its unique molecular structure, featuring both an aldehyde and a phenolic hydroxyl group ortho to a fluorine atom, enables precise chemical modifications for creating high-value intermediates. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical sectors who require specialized fluorinated synthons to develop new active ingredients with enhanced properties.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly in fluorinated active pharmaceutical ingredients (APIs) targeting central nervous system and metabolic diseases.
• Agrochemical Synthesis: Building block for developing advanced herbicides, fungicides, and pesticides where the fluorine atom improves bioavailability and environmental stability.
• Liquid Crystal Materials: Used in the production of fluorinated liquid crystals for high-performance displays, leveraging its rigid, polar structure.
• Organic Electronic Materials: Serves as a starting material for synthesizing fluorinated organic semiconductors and charge-transport materials.
• Complex Ligand Synthesis: Intermediate for creating specialized chelating agents and ligands used in catalysis and metal-organic frameworks (MOFs).
• Fine Chemical & Flavor/Fragrance Intermediate: Used in the tailored synthesis of complex aromatic compounds for specialty chemical applications.

Basic Information

Product Name	2-Fluoro-4-Hydroxybenzaldehyde
CAS No.	348-27-6
Molecular Formula	C7H5FO2
Molecular Weight	140.11 g/mol
Synonyms	4-Hydroxy-2-fluorobenzaldehyde; 2-Fluoro-4-hydroxybenzaldehyde; 2-Fluoro-4-formylphenol; 4-Formyl-3-fluorophenol; 2-Fluoro-p-hydroxybenzaldehyde; 2-Fluor-4-hydroxybenzaldehyd; 2-Fluoro-4-hydroxybenzenecarboxaldehyde; 2-Fluoro-4-hydroxy-benzaldehyde
EINECS	Contact for details

Quality Control

Our 2-Fluoro-4-Hydroxybenzaldehyde is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) detailing all specifications are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber glass or opaque to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	118 - 122 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.