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6-Fluoro (1H)Indazole CAS NO 348-25-4


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CAS No.:348-25-4

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

6-Fluoro (1H)Indazole is a high-purity fluorinated indazole derivative, a versatile heterocyclic building block prized for its role in advanced organic synthesis. Its core value lies in enabling the development of novel molecular architectures, particularly in the pharmaceutical and agrochemical sectors where the introduction of fluorine atoms is a key strategy for modulating bioactivity and metabolic stability. This compound is essential for research chemists and process development scientists working on active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

  • Pharmaceutical Intermediate: A critical precursor in the synthesis of drug candidates, especially kinase inhibitors and other biologically active molecules targeting various therapeutic areas.
  • Agrochemical Research: Used as a key scaffold for developing new herbicides, fungicides, and insecticides, leveraging the fluorine atom to enhance efficacy and environmental profile.
  • Material Science: Serves as a building block for creating specialty polymers, liquid crystals, and organic electronic materials due to its rigid, planar structure.
  • Chemical Biology & Proteomics: Employed in the design of molecular probes, tags, and inhibitors for studying enzyme function and cellular pathways.
  • Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and research organizations for bespoke synthesis projects requiring high-purity fluorinated heterocycles.

Basic Information

Product Name 6-Fluoro (1H)Indazole
CAS No. 348-25-4
Molecular Formula C7H5FN2
Molecular Weight 136.13 g/mol
Synonyms 6-Fluoro-1H-indazole; 1H-Indazole, 6-fluoro-; 6-Fluorindazole; 6-Fluoroindazole; 348-25-4; 6-Fluoro-1H-indazole (6-FI); 6-FI; 6-Fluor-1H-indazol
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Quality Control

Our 6-Fluoro (1H)Indazole is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring high-purity intermediates under cGMP or ISO 9001 frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storage under an inert atmosphere.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Identification (HPLC) Conforms to reference
Purity (HPLC) ≥ 98.0%
Water Content (KF) ≤ 0.5%
Residue on Ignition ≤ 0.1%
Heavy Metals ≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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