Description

DL-Kynurenine CAS NO 343-65-7 is a racemic mixture of the essential amino acid metabolite kynurenine, serving as a critical intermediate in the tryptophan degradation pathway. This compound is of significant value for biochemical research and pharmaceutical development due to its role in modulating immune response and neurological function. It is primarily needed by research institutions, pharmaceutical companies, and diagnostic manufacturers for applications in neuroscience, immunology, and metabolic studies.

Application

• Biochemical Research: Used as a standard and reagent in studies of the kynurenine pathway, neuroinflammation, and neurodegenerative diseases.
• Pharmaceutical Intermediates: Serves as a key building block in the synthesis of more complex neuroactive compounds and potential drug candidates.
• Cell Culture & In Vitro Studies: Employed in media formulations to study cellular metabolism, immune cell regulation, and the effects of tryptophan catabolites.
• Diagnostic Development: Utilized in the development of assays and kits for quantifying kynurenine pathway metabolites in biological samples.
• Metabolic Pathway Analysis: Essential for investigating metabolic disorders and the role of indoleamine 2,3-dioxygenase (IDO) and tryptophan 2,3-dioxygenase (TDO) enzymes.
• Reference Standard: Acts as a high-purity calibrant for analytical techniques like HPLC and LC-MS in academic and quality control laboratories.

Basic Information

Product Name	DL-Kynurenine
CAS No.	343-65-7
Molecular Formula	C10H12N2O3
Molecular Weight	208.21 g/mol
Synonyms	DL-Kynurenine; (±)-Kynurenine; Kynurenine, DL-; 2-Amino-4-(2-aminophenyl)-4-oxobutanoic acid; H-DL-Kyn-OH; NSC 8213; Kynurenine racemate; α-Amino-β-(o-aminobenzoyl)propionic acid; DL-3-(Anthraniloyl)alanine
EINECS	206-430-8

Quality Control

Our DL-Kynurenine is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and development. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%
Optical Rotation	± 0.5° (c=1 in 1N HCl)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.