Description

5'-Fluoro-2'-Hydroxy-2-Phenylacetophenone is a specialized fluorinated aromatic ketone derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both a phenolic hydroxyl and a fluorinated aromatic ring, makes it a valuable intermediate for creating complex molecules with tailored properties. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to synthesize novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of fluorinated drug candidates, particularly for central nervous system (CNS) and anti-inflammatory targets.
• Agrochemical Synthesis: Used in the development of new-generation herbicides and pesticides, where the fluorine atom enhances biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of fluorinated polymers and advanced organic electronic materials for their unique optical and electronic properties.
• Chemical Research & Development: A versatile scaffold for medicinal chemistry and structure-activity relationship (SAR) studies in academic and industrial labs.

Basic Information

Product Name	5'-Fluoro-2'-Hydroxy-2-Phenylacetophenone
CAS No.	343-59-9
Molecular Formula	C14H11FO2
Molecular Weight	230.24 g/mol
Synonyms	2-Hydroxy-5-fluoro-2-phenylacetophenone; 2-Benzoyl-5-fluorophenyl acetate; 5-Fluoro-2-hydroxy-2-phenylacetophenone; 2-(5-Fluoro-2-hydroxyphenyl)-1-phenylethanone; 1-(5-Fluoro-2-hydroxyphenyl)-2-phenylethanone; α-Hydroxy-5-fluoro-α-phenylacetophenone; (5-Fluoro-2-hydroxyphenyl)(phenyl)methanone
EINECS	Contact for details

Quality Control

Our 5'-Fluoro-2'-Hydroxy-2-Phenylacetophenone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure high purity and consistency, meeting the stringent requirements for fine chemical intermediates. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents and bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.