Description

5-Allyl-5-(1-Methylbutyl)-2-Thiobarbituric Acid, Sodium Derivative is a sodium salt derivative of a thiobarbituric acid, a class of compounds historically significant in pharmaceutical chemistry. This compound matters as a key chemical intermediate and reference standard for research and development in medicinal chemistry. It is primarily needed by pharmaceutical R&D laboratories, analytical service providers, and fine chemical manufacturers focused on developing or analyzing central nervous system (CNS) active agents and related barbiturate analogs.

Application

• Pharmaceutical research and development as a chemical intermediate for novel therapeutic agents.
• Analytical chemistry as a reference standard for method development and validation in HPLC or GC analysis.
• Metabolism and pharmacokinetic studies related to thiobarbiturate compounds.
• Academic research in medicinal chemistry for structure-activity relationship (SAR) studies.
• Potential use in the synthesis of specialized ultrashort-acting anesthetic analogs for investigative purposes.
• Quality control and impurity profiling in the manufacturing of related pharmaceutical actives.

Basic Information

Product Name	5-Allyl-5-(1-Methylbutyl)-2-Thiobarbituric Acid, Sodium Derivative
CAS No.	337-47-3
Molecular Formula	C12H17N2NaO2S
Molecular Weight	276.33 g/mol
Synonyms	Sodium 5-Allyl-5-(1-methylbutyl)-2-thiobarbiturate; Thiamylal Sodium; Thioseconal Sodium; 5-Allyl-5-(1-methylbutyl)-2-thiobarbituric acid sodium salt; Surital Sodium; Thioseconal; Thiamylal; Thiobarbituric acid derivative, sodium salt
EINECS	Contact for details

Quality Control

Our 5-Allyl-5-(1-Methylbutyl)-2-Thiobarbituric Acid, Sodium Derivative is produced under a rigorous quality management system. Each batch undergoes comprehensive analytical testing, including identification, assay, and impurity profiling, to ensure it meets precise specifications for research and industrial use. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%; Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.