Description

1-Methyl-L-Histidine is a naturally occurring, methylated derivative of the amino acid L-histidine. This compound is of significant interest in biochemical research and pharmaceutical development due to its role as a potential biomarker and its involvement in metabolic pathways. It serves as a critical building block and reference standard for researchers and manufacturers in the life sciences, nutraceutical, and pharmaceutical industries seeking high-purity biochemicals.

Application

• Biochemical Research: Used as a key reagent and reference standard in metabolic studies, enzyme research, and investigations into histidine metabolism.
• Pharmaceutical Intermediates: Serves as a chiral building block or precursor in the synthesis of more complex pharmaceutical compounds and active ingredients.
• Diagnostic Reagents: Employed in the development and calibration of diagnostic assays and kits, particularly those measuring histidine-related metabolites.
• Nutraceutical Research: Investigated for its potential role and benefits in specialized dietary supplements and clinical nutrition formulations.
• Academic & Industrial Laboratories: A fundamental material for method development, quality control, and analytical testing in various scientific settings.

Basic Information

Product Name	1-Methyl-L-Histidine
CAS No.	332-80-9
Molecular Formula	C7H11N3O2
Molecular Weight	169.18 g/mol
Synonyms	L-1-Methylhistidine; 1-Methylhistidine; Nτ-Methyl-L-histidine; (2S)-2-Amino-3-(1-methyl-1H-imidazol-4-yl)propanoic acid; Hercynine; Thioneine; 1-Methyl-4-imidazolealanine; 332-80-9
EINECS	206-361-5

Quality Control

Our 1-Methyl-L-Histidine is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing all test results are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation	Specific range available on COA
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.