Description

L-Norleucine is a non-proteinogenic, branched-chain amino acid analog that serves as a critical building block in biochemical research and pharmaceutical synthesis. Its unique structure makes it a valuable tool for studying metabolic pathways and for the development of peptide-based therapeutics and diagnostic agents. This high-purity compound is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and nutraceutical industries who require reliable, consistent raw materials for advanced applications.

Application

• Pharmaceutical Intermediates: Key chiral building block in the synthesis of peptide drugs and active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a metabolic probe and standard in studies of amino acid transport, enzyme kinetics, and protein structure-function relationships.
• Cell Culture Media: Component of specialized cell culture formulations for mammalian and microbial fermentation processes.
• Nutritional Science: Employed in research on amino acid metabolism and as a precursor in the development of specialized dietary supplements.
• Peptide Synthesis: A valuable unnatural amino acid residue for constructing modified peptides with enhanced stability or specific biological activity.
• Reference Standard: Serves as a high-purity analytical standard for quality control in pharmaceutical and food testing laboratories.

Basic Information

Product Name	L-Norleucine
CAS No.	327-57-1
Molecular Formula	C6H13NO2
Molecular Weight	131.17 g/mol
Synonyms	(S)-2-Aminohexanoic Acid; L-2-Amino-n-caproic Acid; (S)-Norleucine; L-α-Aminocaproic Acid; Norleucine; H-Nle-OH; L-Hexylglycine; (S)-2-Aminohexanoate
EINECS	206-321-8

Quality Control

Our L-Norleucine is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the high standards required for pharmaceutical and research applications. Certificates of Analysis (COA) detailing purity, specific rotation, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms
Assay (HPLC)	≥ 98.5%
Specific Rotation	+22.0° to +24.0° (c=1 in 1N HCl)
Optical Purity (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.