Description

D-Norleucine CAS NO 327-56-0 is a non-proteinogenic amino acid, specifically the D-isomer of norleucine, which serves as a key chiral building block in organic synthesis and pharmaceutical research. Its value lies in its role as a metabolic analog and a precursor for synthesizing peptides and bioactive compounds with enhanced stability or specific activity. This high-purity chiral intermediate is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors developing novel therapeutics, diagnostic agents, and advanced materials.

Application

• Pharmaceutical Intermediate: Used in the synthesis of peptide-based drugs and active pharmaceutical ingredients (APIs) where the D-configuration confers metabolic stability.
• Biochemical Research: Employed as a standard, inhibitor, or substrate in enzymatic studies and metabolic pathway investigations.
• Peptide Synthesis: A crucial building block for constructing non-natural peptides in drug discovery and development programs.
• Nutritional Science: Utilized in metabolic studies as an analog to study amino acid uptake and utilization.
• Fine Chemical Production: Serves as a chiral synthon for the manufacture of specialty chemicals and complex organic molecules.
• Diagnostic Reagents: Can be incorporated into reagents and kits used for clinical diagnostics and analytical testing.

Basic Information

Product Name	D-Norleucine
CAS No.	327-56-0
Molecular Formula	C₆H₁₃NO₂
Molecular Weight	131.17 g/mol
Synonyms	D-2-Aminohexanoic Acid; (R)-2-Aminohexanoic Acid; D-Homoalanine; D-α-Aminocaproic Acid; (R)-Norleucine; D-Norleucine; D-2-Aminocaproic Acid; (R)-2-Aminocaproic Acid
EINECS	206-321-2

Quality Control

Our D-Norleucine is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including chiral purity assessment by HPLC, to ensure it meets exacting standards for pharmaceutical and research applications. Certificates of Analysis (COA) detailing purity, specific rotation, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% D-isomer
Specific Rotation	Contact for details
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.