Description

2-Fluorophenylalanine is a fluorinated derivative of the essential amino acid phenylalanine, distinguished by the substitution of a fluorine atom on the aromatic ring. This structural modification makes it a critical building block in pharmaceutical research and development, particularly for creating novel peptide-based therapeutics and enzyme inhibitors. It is primarily utilized by research institutions and pharmaceutical companies engaged in drug discovery, proteomics, and the synthesis of bioactive compounds. The compound's unique properties facilitate studies in structure-activity relationships and metabolic pathways.

Application

• Pharmaceutical Intermediate: Key raw material for the synthesis of fluorinated peptide drugs and potential active pharmaceutical ingredients (APIs).
• Proteomics Research: Used as a non-natural amino acid analog to study protein structure, function, and enzyme-substrate interactions.
• Biochemical Tool Compound: Employed in metabolic pathway studies and as a substrate or inhibitor for phenylalanine-metabolizing enzymes.
• Peptide Synthesis: Essential building block in solid-phase and solution-phase peptide synthesis for introducing fluorine atoms into peptide chains.
• Agrochemical Research: Potential intermediate in the development of advanced herbicides and plant growth regulators.
• Diagnostic Agent Development: Used in research for developing radiolabeled compounds for Positron Emission Tomography (PET) imaging.

Basic Information

Product Name	2-Fluorophenylalanine
CAS No.	325-69-9
Molecular Formula	C9H10FNO2
Molecular Weight	183.18 g/mol
Synonyms	(S)-2-Amino-3-(2-fluorophenyl)propanoic Acid; 2-Fluoro-DL-phenylalanine; o-Fluorophenylalanine; 2-F-Phe; F2Phe; 2-Fluorophenylalanine; DL-2-Fluorophenylalanine; (RS)-2-Amino-3-(2-fluorophenyl)propanoic acid
EINECS	206-321-5

Quality Control

Our 2-Fluorophenylalanine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation via IR and NMR spectroscopy. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, detailing all specified parameters to ensure compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Purity (Chiral HPLC)	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.