Description

4-Hydroxy-4'-Fluorobiphenyl is a high-purity biphenyl derivative distinguished by its hydroxyl and fluorine substituents. This compound serves as a versatile and critical advanced intermediate in the synthesis of complex organic molecules, particularly in high-value sectors. It is essential for manufacturers and R&D teams in the pharmaceutical, agrochemical, and liquid crystal material industries seeking reliable, high-quality building blocks.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), especially in non-steroidal anti-inflammatory drugs (NSAIDs) and other therapeutic agents.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, leveraging its biphenyl core for biological activity.
• Liquid Crystal Materials: Serves as a fundamental precursor in the manufacture of fluorinated liquid crystals for display technologies (LCDs).
• Polymer Science: Acts as a monomer or modifier in the synthesis of specialty polymers and engineering plastics to enhance thermal and chemical resistance.
• Organic Electronic Materials: Investigated for use in organic light-emitting diodes (OLEDs) and other electronic applications due to its conjugated structure.
• Research & Development: A valuable compound for academic and industrial R&D in medicinal chemistry and material science.

Basic Information

Product Name	4-Hydroxy-4'-Fluorobiphenyl
CAS No.	324-94-7
Molecular Formula	C₁₂H₉FO
Molecular Weight	188.20 g/mol
Synonyms	4'-Fluoro-4-biphenylol; 4-(4-Fluorophenyl)phenol; [1,1'-Biphenyl]-4-ol, 4'-fluoro-; p-Hydroxy-p'-fluorobiphenyl; 4-Fluoro-4'-hydroxybiphenyl; 4-(4-Fluorophenyl)phenol; 4'-Fluorobiphenyl-4-ol
EINECS	206-300-6

Quality Control

Our 4-Hydroxy-4'-Fluorobiphenyl is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications. Our quality commitment aligns with cGMP principles where applicable, ensuring reliability for critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The product is light-sensitive and should be stored away from direct light exposure.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	162 - 166 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.