Description

2-Fluorobenzal Chloride is a versatile and reactive organofluorine building block, also known by its CAS number 320-65-0. This compound is valued for its bifunctional reactivity, featuring both a benzal chloride and a fluorine substituent, which makes it a critical intermediate in advanced synthetic pathways. It is primarily sought after by research chemists and process development teams in the pharmaceutical and agrochemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of fluorinated active pharmaceutical ingredients (APIs), including potential candidates for central nervous system (CNS) drugs and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the development of novel fluorinated pesticides and herbicides, where the fluorine atom can enhance biological activity, stability, and selectivity.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorinated aromatic compounds used in electronic display technologies and organic light-emitting diodes (OLEDs).
• Functional Dye Chemistry: Employed in the production of specialized fluorinated dyes and pigments with unique optical properties.
• Cross-Coupling Reactions: Acts as an electrophile in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) to introduce fluorinated benzyl motifs.
• Chemical Research & Development: A valuable reagent for exploring new fluorination methodologies and creating fluorinated analogs in medicinal chemistry programs.

Basic Information

Product Name	2-Fluorobenzal Chloride
CAS No.	320-65-0
Molecular Formula	C7H5Cl2F
Molecular Weight	179.02 g/mol
Synonyms	α,α-Dichloro-2-fluorotoluene; 2-Fluorobenzylidene Chloride; (Dichloromethyl)-2-fluorobenzene; 2-Fluorobenzal Dichloride; 2-Fluorobenzyl Dichloride; 1-(Dichloromethyl)-2-fluorobenzene; o-Fluorobenzal Chloride
EINECS	206-276-6

Quality Control

Our 2-Fluorobenzal Chloride is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support cGMP and ISO 9001 standards for pharmaceutical and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent hydrolysis. Keep away from strong acids and incompatible organic solvents.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC)	≤ 2.0% total

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.