Description

4-Chloro-Alpha,Alpha,α-Trifluoro-m-Toluidine is a halogenated aniline derivative that serves as a critical fluorinated aromatic intermediate in advanced organic synthesis. Its unique structure, featuring both chloro and trifluoromethyl substituents, provides exceptional reactivity and stability for constructing complex molecules. This compound is essential for research and development chemists and process engineers in the agrochemical and pharmaceutical industries, where it is used to synthesize novel active ingredients and fine chemicals.

Application

• Agrochemical Intermediate: A key building block for the synthesis of advanced herbicides, fungicides, and insecticides, leveraging the biological activity of the trifluoromethyl group.
• Pharmaceutical Intermediate: Used in the research and production of active pharmaceutical ingredients (APIs), particularly those requiring fluorinated aromatic motifs for enhanced metabolic stability and bioavailability.
• Dye and Pigment Synthesis: Serves as a precursor for specialty dyes and pigments, where the chloro and trifluoromethyl groups influence color properties and fastness.
• Liquid Crystal & Electronic Chemicals: Employed in the synthesis of fluorinated components for liquid crystal displays (LCDs) and other electronic materials.
• Polymer Modification: Acts as a monomer or modifier in the production of specialty polymers with tailored chemical resistance and surface properties.
• Cross-Coupling Reactions: A valuable substrate in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) for creating complex biaryl structures.

Basic Information

Product Name	4-Chloro-Alpha,Alpha,α-Trifluoro-m-Toluidine
CAS No.	320-51-4
Molecular Formula	C7H5ClF3N
Molecular Weight	195.57 g/mol
Synonyms	4-Chloro-3-(trifluoromethyl)aniline; 3-Amino-6-chlorobenzotrifluoride; 4-Chloro-α,α,α-trifluoro-m-toluidine; 4-Chloro-3-trifluoromethylaniline; 2-Chloro-5-aminobenzotrifluoride; 5-Amino-2-chlorobenzotrifluoride; m-Toluidine, 4-chloro-α,α,α-trifluoro-; Benzenamine, 4-chloro-3-(trifluoromethyl)-
EINECS	206-277-3

Quality Control

Our 4-Chloro-Alpha,Alpha,α-Trifluoro-m-Toluidine is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment ensures the material is suitable for demanding applications in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	68 - 72 °C
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.