Description

2,4-Bis(Trifluoromethyl)-6-Nitroaniline is a high-value, multi-functional aromatic amine building block characterized by its electron-deficient aromatic ring and trifluoromethyl substituents. This compound matters for its role as a critical precursor in the synthesis of advanced materials and active pharmaceutical ingredients (APIs), where its unique structure imparts desirable properties like enhanced stability and lipophilicity. It is primarily needed by R&D chemists and process development teams in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel compounds and fine-tuning molecular properties.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in areas targeting central nervous system (CNS) disorders and anti-infectives.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and pesticides, where the trifluoromethyl groups contribute to biological activity and environmental persistence.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Functional Material Research: Incorporated into the design of organic electronic materials, such as non-linear optical (NLO) chromophores and charge-transport materials.
• Dye and Pigment Intermediate: Utilized in the synthesis of high-performance, light-fast dyes and pigments for specialized applications.
• Fluorinated Compound Library: An essential building block for constructing diverse fluorinated compound libraries for high-throughput screening in drug discovery.

Basic Information

Product Name	2,4-Bis(Trifluoromethyl)-6-Nitroaniline
CAS No.	320-21-8
Molecular Formula	C8H4F6N2O2
Molecular Weight	274.12 g/mol
Synonyms	6-Nitro-2,4-bis(trifluoromethyl)aniline; 2,4-Bis(trifluoromethyl)-6-nitrobenzenamine; 2,4-Bis(trifluoromethyl)-6-nitro-phenylamine; 2,4-Bis(trifluoromethyl)-6-nitroaniline; 6-Nitro-α,α,α,α',α',α'-hexafluoromesidine; Benzenamine, 2,4-bis(trifluoromethyl)-6-nitro-; 320-21-8 (CAS)
EINECS	Contact for details

Quality Control

Our 2,4-Bis(Trifluoromethyl)-6-Nitroaniline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and commercial synthesis. Certificates of Analysis (COA) detailing batch-specific results are available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases. For long-term storage, consider an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.