Description

7-Fluoroisatin is a versatile fluorinated heterocyclic building block, a key intermediate in modern organic synthesis. Its value lies in the unique reactivity of the isatin core combined with the electronic effects of the fluorine substituent, enabling precise molecular construction. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of fluorinated drug candidates, including kinase inhibitors, anticancer agents, and central nervous system (CNS) active compounds.
• Agrochemical Synthesis: Used to develop novel fluorinated pesticides and herbicides, where the fluorine atom enhances biological activity, stability, and metabolic properties.
• Organic Synthesis Building Block: Serves as a starting material for constructing complex heterocycles like quinolones, indoles, and other fused ring systems via condensation and cyclization reactions.
• Material Science Research: Employed in the development of organic semiconductors, dyes, and fluorescent markers due to its conjugated structure and photophysical properties.
• Biochemical Probe Development: Utilized in medicinal chemistry to create fluorinated probes and inhibitors for studying enzyme mechanisms and biological pathways.

Basic Information

Product Name	7-Fluoroisatin
CAS No.	317-20-4
Molecular Formula	C8H4FNO2
Molecular Weight	165.12 g/mol
Synonyms	7-Fluoro-1H-indole-2,3-dione; 7-Fluoroindole-2,3-dione; 7-Fluoro-2,3-dioxoindoline; 7-Fluoro-2,3-dihydro-1H-indole-2,3-dione; 7-Fluoroisatin; 7-Fluorooxindole; 7-Fluoro-2,3-indolinedione
EINECS	Contact for details

Quality Control

Our 7-Fluoroisatin is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high purity and consistent performance. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.