Description

2'-Fluoro[1,1'-Biphenyl]-2-Amine is a specialized biphenyl derivative featuring a fluorine substituent and an amine functional group, making it a valuable fluorinated aromatic building block. This compound is crucial for the synthesis of complex molecules where its unique electronic and steric properties can significantly influence biological activity and material characteristics. It is primarily sought after by research and development teams in the pharmaceutical, agrochemical, and advanced materials sectors for use in drug discovery, ligand synthesis, and the creation of novel organic electronic materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and pesticides, where the fluorine atom enhances metabolic stability and bioavailability.
• Ligand & Catalyst Development: Serves as a precursor for nitrogen-containing ligands used in transition metal catalysis for cross-coupling and other organic transformations.
• Material Science Research: Employed in the synthesis of fluorinated organic semiconductors, liquid crystals, and polymers for electronic and optoelectronic applications.
• Chemical Reference Standard: Utilized as a high-purity analytical standard in quality control laboratories for method development and validation.
• Academic & Industrial R&D: A versatile building block for exploratory chemistry in medicinal and synthetic organic chemistry programs.

Basic Information

Product Name	2'-Fluoro[1,1'-Biphenyl]-2-Amine
CAS No.	316-61-0
Molecular Formula	C12H10FN
Molecular Weight	187.21 g/mol
Synonyms	[1,1'-Biphenyl]-2-amine, 2'-fluoro-; 2-Amino-2'-fluorobiphenyl; 2'-Fluoro-2-aminobiphenyl; 2'-Fluorobiphenyl-2-amine; 2-(2-Fluorophenyl)aniline; o-Amino-o'-fluorobiphenyl; 2-Biphenylamine, 2'-fluoro-; 316-61-0
EINECS	206-263-6

Quality Control

Every batch of 2'-Fluoro[1,1'-Biphenyl]-2-Amine is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the product meets the high-purity requirements for research and industrial synthesis. A detailed Certificate of Analysis (COA) is supplied with each shipment, confirming identity, purity, and impurity profiles as determined by advanced chromatographic and spectroscopic methods.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.