Description

2,2,2-Trifluoro-1-o-Tolyl-Ethylamine Hcl is a high-purity fluorinated amine hydrochloride salt, a key building block in advanced organic synthesis. Its trifluoromethyl group and aromatic amine structure make it a valuable intermediate for introducing lipophilicity and metabolic stability into target molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of active pharmaceutical ingredients (APIs), especially those targeting central nervous system (CNS) disorders.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides where the trifluoromethyl group enhances biological activity.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated compounds used in electronic display technologies.
• Organic Synthesis Reagent: Employed in academic and industrial R&D for constructing complex molecules via amination and coupling reactions.
• Fluorine Chemistry Research: A standard compound for studying the effects of fluorine substitution on chemical and physical properties.

Basic Information

Product Name	2,2,2-Trifluoro-1-o-Tolyl-Ethylamine Hcl
CAS No.	315-43-5
Molecular Formula	C9H11ClF3N
Molecular Weight	225.64 g/mol
Synonyms	α-Methyl-2-(trifluoromethyl)benzylamine hydrochloride; 1-(2-Methylphenyl)-2,2,2-trifluoroethylamine hydrochloride; o-Tolyl(trifluoroethyl)amine HCl; 2,2,2-Trifluoro-1-(2-methylphenyl)ethanamine hydrochloride; 1-(2-Methylphenyl)-2,2,2-trifluoroethanamine hydrochloride; Benzenemethanamine, α-(trifluoromethyl)-2-methyl-, hydrochloride; (RS)-2,2,2-Trifluoro-1-o-tolylethylamine hydrochloride
EINECS	Contact for details

Quality Control

Our 2,2,2-Trifluoro-1-o-Tolyl-Ethylamine Hcl is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and Karl Fischer titration, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specifications and test results. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere or in a desiccator after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.