Description

Apomorphine Hydrochloride is a potent dopamine agonist used primarily in pharmaceutical applications. This compound is critical for its therapeutic effects in managing specific neurological conditions, offering reliable and consistent performance in formulation. It is essential for manufacturers in the pharmaceutical and advanced research sectors who require high-purity active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical API: Primary use as the active ingredient in medications for Parkinson's disease, specifically for the treatment of acute "off" episodes.
• Neurological Research: Used as a standard dopamine D1 and D2 receptor agonist in preclinical and clinical neuroscience studies.
• Drug Formulation: Serves as a key component in the development of injectable solutions and other controlled-release delivery systems.
• Chemical Synthesis: Acts as a sophisticated intermediate or reference standard in the synthesis of related dopaminergic compounds.
• Analytical Standard: Employed as a high-purity calibrant in HPLC, LC-MS, and other analytical methods for quality control and pharmacokinetic studies.

Basic Information

Product Name	Apomorphine Hydrochloride
CAS No.	314-19-2
Molecular Formula	C17H17NO2 • HCl
Molecular Weight	303.79 g/mol (Free base: 267.33 g/mol)
Synonyms	(R)-Apomorphine Hydrochloride; 6aβ-Aporphine-10,11-diol Hydrochloride; Apomorphine HCl; R(-)-Apomorphine Hydrochloride; APO HCl; U-42585E; (R)-(-)-10,11-Dihydroxyaporphine Hydrochloride; 5,6,6a,7-Tetrahydro-6-methyl-4H-dibenzo[de,g]quinoline-10,11-diol Hydrochloride
EINECS	206-250-3

Quality Control

Our Apomorphine Hydrochloride is manufactured under strict quality systems. It undergoes comprehensive analytical testing to ensure it meets high-purity standards suitable for pharmaceutical use, including identity, purity, and impurity profile verification. A Certificate of Analysis (COA) detailing batch-specific results is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; appropriate handling procedures should be followed to maintain stability and potency.

Specification

Item	Specification
Appearance	White to grayish-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%
Specific Rotation	-40° to -46° (c = 1 in H2O)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.