Description

2,6-Bis(Trifluoromethyl)Aniline is a high-value fluorinated aromatic building block characterized by its electron-deficient aniline core flanked by two trifluoromethyl groups. This unique structure makes it a critical intermediate for synthesizing advanced materials and active pharmaceutical ingredients (APIs) where enhanced lipophilicity, metabolic stability, and electronic properties are required. It is primarily sought by R&D and production chemists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly for kinase inhibitors and other targeted therapies where the trifluoromethyl groups improve bioavailability and binding affinity.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides, leveraging its ability to modulate the physicochemical properties of active ingredients.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science: Building block for fluorinated polymers, liquid crystals, and organic electronic materials that require specific dielectric constants and thermal stability.
• Dye and Pigment Industry: Intermediate for synthesizing specialized fluorinated dyes with unique color fastness and solubility properties.

Basic Information

Product Name	2,6-Bis(Trifluoromethyl)Aniline
CAS No.	313-13-3
Molecular Formula	C8H5F6N
Molecular Weight	229.13 g/mol
Synonyms	2,6-Bis(trifluoromethyl)benzenamine; 2,6-Bis(trifluoromethyl)phenylamine; α,α,α,α',α',α'-Hexafluoro-2,6-xylidine; 2-Amino-1,3-bis(trifluoromethyl)benzene; 2,6-Di(trifluoromethyl)aniline; Benzenamine, 2,6-bis(trifluoromethyl)-; 2,6-BTFA
EINECS	206-227-8

Quality Control

Our 2,6-Bis(Trifluoromethyl)Aniline is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets the high standards required for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, impurity profile, and physical characteristics is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	34 - 38 °C
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.